Genetic analysis of virulence of Streptococcus pneumoniae.
Duplicate Title to Stress response proteins in Streptococcus pneumoniae Retired, Enlighten Team - ( Manage ) ( Acknowledge ).
This thesis concerns the structural and biochemical characterisation of DacB, herein renamed to LdcB (LD-carboxypeptidase B). The crystal structures of the apo form of LdcB from both S. pneumoniae and Bacillus subtilis were solved, revealing a single domain, globular protein with 2 sub-domains forming a V-shaped cleft in which the active site is located.
Naturally competent bacterial species, which self-induce the recombination mechanism of transformation, are wide spread across the bacterial tree-of-life. However, it remains unclear why competence has evolved in these bacteria. Although it is likely that exact explanations will be different for each species, a common selective factor cannot be excluded.
PhD thesis, University of Warwick. Abrahams, Katherine A. (2011) The enzymology of Streptococcus pneumoniae peptidoglycan polymerisation. PhD thesis, University of Warwick. B. Borsetto, Chiara (2017) Study and exploitation of diverse soil environments for novel natural product discovery using metagenomic approaches. PhD thesis, University of.
Thesis or Dissertation. Peswani, Rahul Lekhraj (2018) Mechanisms regulating adult neurogenesis in the hypothalamus using a genetic inducible-approach to label and optogenetically stimulate hypothalamic neural progenitors. PhD thesis, University of Warwick. Natale, Alessandra Pia (2010) Genotypic and phenotypic flexibility of microbial communities.
Streptococcus pneumoniae is an asymptomatic colonizer of the nasopharynx and is a major cause of a diverse array of infections, including pneumonia, meningitis, bacteremia, sinusitis, and otitis media. The organism causes infection either by direct extension from the nasopharynx, leading, for example, to pneumonia or otitis media, or by invasion into normally sterile fluids, leading to.
PhD thesis, University of Liverpool. Zhao, Q (2017). Jacques, LC (2017) Investigating the role of Streptococcus pneumoniae serotype 1 virulence factors in nasopharyngeal carriage and invasive disease. PhD thesis, University of Liverpool. Taietti, GD (2017).